Gene editing will be used to create hypoallergenic cats!


CRISPR gene editing was used to remove two genes encoding a protein that is primarily responsible for allergy reactions in cats. According to InBio, a US-based business, this is the first step toward generating hypoallergenic cats.

Nicole Brackett, who leads InBio’s CRISPR cat team, said, “The expected timetable for this is several years.”


Cats cause allergic responses in about 15% of humans. A tiny protein called Fel d 1 is released by salivary and cutaneous glands and is the main source of this. It is dispersed across cats’ fur when they groom themselves. As the fur dries, it can become airborne. It’s unclear what, if anything, Fel d 1 does for cats.

All cats secrete Fel d 1. A 2019 study found that levels in saliva vary greatly among typical domestic cats. It is often noticed that some specific breeds are less likely to trigger allergies. But, no scientific studies have currently support this or verify it.

Gene Editing Explained

Fel d 1 is made up of two subunits. Each of which is encoded by two distinct genes (CH1 and CH2). Many differences were discovered when Brackett and her colleagues compared the sequences of the CH1 and CH2 genes in domestic cats to those in other cat species such as lions, tigers, cougars, and fishing cats.

This shows that Fel d 1 isn’t required since the sequence of important functional genes changes very little, if at all. The only way to know for sure is to observe what happens to cats who are unable to make any Fel d 1.

“At the moment, we don’t have any specific cat breeds in mind,” Brackett explains.

At least two other firms declared plans to modify moggies to eliminate Fel d 1 in the 2000s. None of them were successful. However, because of the development of CRISPR in 2012, achieving this is now more achievable.

Various firms are looking at other ways to reduce Fel d 1. Such as developing a vaccine that causes cats to produce antibodies that bind to Fel d 1 before it is secreted.



Please enter your comment!
Please enter your name here





Sally, The Mermaid Cat Recovers After Being Shot in Head

Sally, the mermaid cat was three months old when shot in the head and left for dead in a nearby park in 2013. The...

Chester Zoo Welcomes a Rare Baby Wallaby from its Mother’s Pouch

Chester Zoo is one of only four zoos in the UK that care for dusky pademelons. Across Europe only 56 live in zoos. Recently...

Guinness World Records Declared the World’s Oldest Dog

A 21-YEAR-OLD Chihuahua TobyKeith from Florida has been named the world's oldest dog. The news about TobyKeith, who was born on January 9, 2001,...

Largest Ever Crown Jellyfish Discovered that Looks Like an Alien Saucer

In the "midnight zone" of California's Monterey Bay, scientists have discovered a new species of crown jellyfish that resembles a crimson alien spaceship. According...

Camel Born At Amersfoort Zoo

Amersfoort Zoo has reported the birth of a baby camel. The camel was delivered early in the morning. Moreover, the birth took place on...